How does the Chronic Renal Failure Cause Heart Failure

Chronic Renal Failure (CRF) will have an influence on heart and may lead to Heart Failure which is a main complication of CRF. Many factors can contribute to Heart Failure, containing:

(1) Excessive blood volume: during the CRF, all of blood volume, left ventricular end-diastolic volume, heart stroke volume and cardiac output will increase. When the heart function can't play its compensatory role, left ventricular function will decline, which can give rise to the Renal Failure.

(2) Hypertension: the long-term of Hypertension can overload the heart and cause ventricular hypertrophy and heart enlargement. Further the Heart Failure will occur. In addition, Hypertension also can accelerate the development of atherosclerosis.

(3) The uremic toxins: during the CRF, toxins will be accumulated in human body and inhibit myocardium, causing myocardial lesion. This also can lead to the occurrence of Heart Failure.

(4) Electrolyte disorder and acidosis: the electrolyte disorder can change the electrical and myocardial excitability and induce the arrhythmia and Heart Failure.

(5) Renal Anemia: the long-term Anemia can induce myocardial hypoxia and the decline of myocardial function.

(6) Atherosclerosis: both hypertension-one of the complications of CRF and hyperlipidemia occurring after the dialysis can accelerate the development of the atherosclerosis, increasing the death rate of CRF. Some patients may die from the myocardial infarction during the dialysis.

(7) Low immunity: the low immunity during uremic easily induces infection and myocarditis, resulting in Heart Failure.