What are the Symptoms of End-Stage Renal Disease

End-Stage Renal Disease (ESRD) is almost the complete failure of the kidneys to function. The main function of the kidneys is to filter wastes, toxins and excess water from the body. So, once the kidney disease enters into end-stage renal failure, which kind of symptoms will the end-stage renal failure have?

End stage renal failure symptoms may include:
Weight loss without trying
Generalized itching (pruritus) and dry skin
Loss of appetite
Headaches
Nausea
General ill feeling and fatigue
What Other symptoms the end-stage renal failure may develop? The follows are for you to refer:
Swelling of the feet and hands (edema)
Bone pain
Brain and nervous system symptoms
Drowsiness and confusion
Problems concentrating or thinking
Numbness in the hands, feet, or other areas
Muscle twitching or cramps
Abnormally dark or light skin and changes in nails
Easy bruising, nosebleeds, or blood in the stool
Breath odor
Excessive thirst
Low level of sexual interest and impotence
Frequent hiccups
Sleep problems, such as insomnia, restless leg syndrome, or obstructive sleep apnea
Menstrual periods stop (amenorrhea)
Vomiting, especially in the morning

Can Renal Failure Be Cured

I would like to ask you please: Is it possible in my case to be cured completely, and thus I can stop dialysis and get rid of it totally.

Expert's reply:
I read the Test Report you sent me again, and I’m sure there is no report about your Renal Function including Serum Creatinine and Glomerular Filtration Rate. Please tell me how many times the dialysis in one week. These indexes are very important. As a responsible doctor, I cannot promise you anything without even knowing how much is your remaining renal function. However, I can surely tell you that as long as your remaining renal function is more than 10%, our treatment will be much helpful.
We have help many patients with similar disease condition to you. A patient with Renal Failure will leave our hospital happily today. When he came to our hospital, his total urine volume was only 200ml, but after the treatment, it rises to 700ml. You told me your urine is 1000ml/24hours. Your condition is much better than him, so I believe better effect will be achieved.
The treatment of Micro-Chinese Medicine Osmotherapy and Immunotherapy can help repair the damaged kidney inherent cells and protect the remaining renal function. That is to say, if you have 60% renal function, our treatment can ensure that the 60% will not be damaged and we can recover more of the renal function. The effect can be 70%, 80% or 90% of your renal function can be rebuilt, but for the 10% that had already died, no one can make it live again. Do you think the disease is completely cured or not? We have treated many patients with Renal Failure, and many of them have got rid of dialysis.
You know the effect of any treatment is different with different people. Some patients are sensitive to our medicine, while some patients are less sensitive due to weak physique or other factors. However, as long as the patients continue with the treatment, the effect will be significant. Many patients live a normal life after the treatment and many can survive as a benign kidney disease carrier.
We are very confident in treating your disease. I hope you feel the same, too.
If you need any help, please email to khkpcn@hotmail.com.

Food Forbidden with Chronic Renal Failure

Chronic Renal Failure refers to the process of renal progressive damage and gradual deterioration of renal function caused by a variety of primary kidney diseases or secondary diseases. When the development of renal damage cannot maintain the balance of inner environment of the body, it will result in the retention of toxic metabolites, water, electrolyte and acid-base disorders and then a series of clinical symptoms.
For Chronic Renal Failure patients, besides proper treatment, reasonable diet is also very important.
Food forbidden with Chronic Renal Failure is as follows.
First, stimulating foods
Second, beans and beans products: beans, bean sprouts, lentils, red beans, mung beans, broad beans, peas, tofu, etc.;
Third, internal organs of animals (heart, liver, spleen, lung, large intestine, small intestine, stomach, etc.);
Fourth, spicy foods and spices: chives, celery, parsley, garlic, pepper, onion, ginger, packaged spices, star anise, cumin, soy sauce, vinegar and so on;
Fifth, high-protein foods: milk, soybean milk powder, oatmeal, black sesame paste, eggs, duck eggs, goose eggs, quail eggs, beef, snake, etc.;
Sixth, high animal fat foods: fat, etc.;
Seventh, edible oil: lard, soybean oil, salad oil, peanut oil, cooking oil, etc.;
Eighth, nuts food: walnuts, peanuts, chestnut, melon seeds, pistachios, water chestnuts and so on.

What is Creatinine and What Does it Mean if Your Creatinine is High

Many tests may be performed to evaluate the function of the body’s major organs if people have discomforts. If the blood or urine tests show that the serum creatinine is high, it means that there are some problems of your kidneys.

Creatinine is a chemical waste molecule that is produced from muscle metabolism. It is filtered from the body by the kidneys in the process of urination. The creatinine levels in the body are important determinants of kidney function. Unusually, high creatinine levels may have a drastic effect on the kidneys and may even lead to kidney failure, because not enough creatinine is being excreted by the kidneys.

The normal range of serum creatinine for male is 53～106 umol/l (0.6～1.2mg/dl); and for female is 44～97 umol/l(0.5～1.1 mg/dl).
What does the test result mean?

Increased creatinine levels in the blood suggest diseases or conditions that affect kidney function. These can include:
Damage to or swelling of blood vessels in the kidneys caused by infection or autoimmune diseases etc.
Bacterial infection of the kidneys (pyelonephritis)
Death of cells in the kidneys’ small tubes (acute tubular necrosis) caused, for example, by drugs or toxins
Prostate disease, kidney stone, or other causes of urinary tract obstruction
Reduced blood flow to the kidney due to shock, dehydration, congestive heart failure, atherosclerosis, or complications of diabetes
High blood creatinine is usually a sign of problems with kidney functions.
Serum creatinine is also the major component in the various equations used to estimate GFR, and as a patient, it is what you will use most in tracking how your kidney function is doing.

Serum Creatinine and Kidney Failure

Creatinine is one of the indexes during renal function test. Measuring serum creatinine is a useful and inexpensive method of evaluating renal dysfunction. Creatinine is a non-protein waste product of creatine phosphate metabolism by skeletal muscle tissue. Creatinine production is continuous and is proportional to muscle mass.

Creatinine is freely filtered and therefore the serum creatinine level depends on the Glomerular Filtration Rate (GFR). Renal dysfunction diminishes the ability to filter creatinine and the serum creatinine rises. If the serum creatinine level doubles, the GFR is considered to have been halved. A threefold increase is considered to reflect a 75% loss of kidney function.

Reference values for serum creatinine:
Adult males: 0.8 - 1.4 mg/dl: values are slightly higher in males due to larger muscle mass
Adult females: 0.6 - 1.1 mg/dl: creatinine clearance is increased in pregnancy, resulting in lower serum levels
Children: 0.2 - 1.0 mg/dl: slight increases with age because values are proportional to body mass
A panic value for creatinine is 10 mg/dl in nondialysis patients.
Decreased creatinine levels may be seen in: the elderly, persons with small stature, decreased muscle mass, or inadequate dietary protein. Muscle atrophy can also result in decreased serum creatinine level. If muscle atrophy is suspected, assessment of serum creatine, an important enzyme necessary for normal muscle function, is done.
The only important pathological condition that causes a significant increase in the serum creatinine level is damage to a large number of nephrons. Unlike the BUN, the serum creatinine level is not affected by hepatic protein metabolism. Tests to measure serum creatinine, urine creatinine, and creatinine clearance are all used only to evaluate renal function. Only renal dysfunction changes the results. The serum creatinine level does not rise until at least half of the kidney's nephrons are destroyed or damaged. Because creatinine levels rise and fall more slowly than BUN levels, creatinine levels are often preferred to monitor renal function on a long-term basis.
Increased serum creatinine levels are seen in: Impaired renal function, Chronic Nphritis, Urinary tract obstruction, Muscle diseases such as gigantism, acromegaly, and myasthenia gravis, Congestive heart failure, and shock.

Healthy Diet for Stage 3 CKD

Diet is such an important part of treatment. Eating a proper diet can help preserve kidney function and overall health.

A healthy diet for stage 3 CKD may recommend:

Including a variety of grains, fruits and vegetables, but whole grains and some fruits and vegetables may be limited if blood tests show phosphorus or potassium levels are above normal.

A diet that is low in saturated fat and cholesterol and moderate in total fats, especially if cholesterol is high or if you have diabetes or heart disease

Limiting intake of refined and processed foods high in sodium and prepare foods with less salt or high sodium ingredients

Aiming for a healthy weight by consuming adequate calories and including physical activity each day

Keeping protein intake within the DRI level recommended for healthy people with attention to high quality protein.

Consuming the DRI for the water soluble vitamin B complex and C.
Vitamin D and iron may be tailored to individual requirements
Limiting phosphorus if blood levels of phosphorus or PTH (Parathyroid Hormone) are above normal

Limiting calcium if blood levels are above normal

Potassium is usually not restricted unless blood levels are above normal

Symptoms of Stage 3 Chronic Kidney Failure

A person with Stage 3 CKD has kidney damage with a moderate decrease in the GFR of 30-59 ml/min. As kidney function declines waste products can build up in the blood causing a condition known as “uremia.” In Stage 3 Chronic Kidney Failure a person is more likely to develop complications of kidney disease such as high blood pressure, anemia (a shortage of red blood cells) and/or early bone disease.

Symptoms of Stage 3 Chronic Kidney Failure, such as:

Fatigue and Anemia: Feeling tired is common for people with CKD and is often caused by anemia. anemia often develops during stage 3 kidney disease. Because the red blood cells carry oxygen throughout the body, a decrease in red blood cells reduces the amount of oxygen. With less circulating oxygen, the cells in the body must work harder, which causes fatigue.

Too much fluid: The kidneys may lose their ability to control how much fluid stays in the body. A person may notice swelling (edema) in their lower legs, hands or face around the eyes. With too much fluid someone could even feel short of breath.

Urination changes: Urine may be foamy if there is protein in it, or dark orange, brown, tea colored or red if it contains blood. A person may urinate more or less, or get up at night to go to the bathroom.
Kidney pain: Most people with CKD do not have kidney pain, but with some kinds of kidney problems, such as polycystic kidney disease or infections, they may have pain in their back where the kidneys are.

Sleep problems: Some people have trouble falling asleep or staying asleep. Itching, muscle cramps or restless legs can keep them awake.

High Blood Pressure: Blood pressure is the force of the blood against the blood vessel walls, as described by the National Kidney and Urologic Diseases Information Clearinghouse. There are many factors that can affect blood pressure, and the kidneys play a key role in maintaining a healthy blood pressure. As the kidneys begin to fail, fluids build up in the body, which increases the volume of blood. An increase in blood volume within the blood vessels creates more pressure on the vessel walls, translating to an increase in blood pressure. This is part of a dangerous cycle, as high blood pressure damages the blood vessel walls. When the blood vessels in the kidney are damaged, it contributes to the kidney damage, causing further loss of function.